In order to solve the problem of intercellular eavesdropping in Device to Device (D2D) communication, an anti-eavesdropping secure transmission scheme based on artificial noise assisted Time-Reversal (TR) was proposed. Firstly, the interference between cells was eliminated under the cross-cell channel model. Secondly, the ability of eavesdropping users to steal information was deteriorated by sending artificial noise to the base station to assist TR technology. Finally, in order to meet the needs of cellular users for service quality and maximize the system traversal secrecy rate, the power control allocation scheme with convex optimization was adopted to maximize the transmitted power of D2D users. Through simulation experiment analysis, compared with the artificial noise scheme, this scheme improves the achievable secrecy rate of 0.8 b·s^-1·Hz^-1 under the same Signal-to-Noise Ratio (SNR). In addition, with the increase of the number of neighboring cells, this scheme has improvement on the reachable secrecy rate more and more obvious.